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Description
| Pack Size | 5G |
|---|---|
| Storage Temperature | 4-8 degree C |
| Note | This product is for research use only. |
| Description | Sodium Hyaluronate is the sodium salt of hyaluronic acid (HA), also known as hyaluronan, a glycosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units. HA is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. HA is a naturally occurring biopolymer involved in numerous biological processes including tissue hydration and structural scaffolding. HA is increasingly used as a reagent and investigated in medical, pharmaceutical and bioengineering applications. Its use as a reagent includes hydrogels for use in aesthetics, ophthalmology, rheumatology, urology, wound healing, and 3D bioprinting. Our medical grade Sodium Hyaluronate is produced by HTL by fermentation of a <em>Streptococcus equi</em> strain (Group C of the Lancefield Classification / Non GMO / Without any material from animal origin). HTL’s proprietary process allows the production of Sodium Hyaluronate fiber with an exceptionally low level of impurities. HTL Sodium Hyaluronate raw material is a medical grade pharmaceutical product manufactured under cGMP conditions and is covered by a Certificate of Suitability of Monographs if the European Pharmacopoeia (CEP) and Drug Master File (DMF). HTL Sodium Hyaluronate is aliquoted and distributed by Echelon for research use only. <strong>Storage:</strong> dry product at 5 °C, protected from light and humidity. Solutions should be stored frozen at -20 °C or below. <strong>About HTL:</strong> HTL is the world leader in the production of pharmaceutical grade Sodium Hyaluronate by fermentation. <a href="https://htlbiotech.com/characteristics/">www.htlbiotech.com</a> Bulk discounts available, please email <a href="mailto:echelon@echelon-inc.com?subject=Bulk">echelon@echelon-inc.com</a> for information. <hr /> <h4>References</h4> 1) M.A. Serban, A. Skardal (2018) “<a href="https://www.sciencedirect.com/science/article/pii/S0945053X17304547">Hyaluronan chemistries for three-dimensional matrix applications</a>” Matrix Biology, 78-79, 337-3454. doi: 10.1016/j.matbio.2018.02.010. 2) C.B. Highley, G.D. Prestwich GD, Burdick JA. (2016) “<a href="https://www.sciencedirect.com/science/article/pii/S0958166916300313">Recent advances in hyaluronic acid hydrogels for biomedical applications</a>.” Curr Opin Biotechnol. 40, 35-40. doi: 10.1016/j.copbio.2016.02.008. 3) J.A. Burdick, G.D. Prestwich (2011) “<a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201003963">Hyaluronic acid hydrogels for biomedical applications</a>.” Adv Mater. 23, H41-56. doi: 10.1002/adma.201003963. 4) A. Dodero, R. Williams, et al. (2019) “<a href="https://www.sciencedirect.com/science/article/pii/S0144861718311470">A micro-rheological and rheological study of biopolymers solutions: Hyaluronic acid</a>” Carbohydrate Polymers, 203, 349-355, doi:10.1016/j.carbpol.2018.09.072. 5) P.A. Simmons, J.G. Vehige (2017) “<a href="https://www.dovepress.com/investigating-the-potential-benefits-of-a-new-artificial-tear-formulat-peer-reviewed-article-OPTH">Investigating the potential benefits of a new artificial tear formulation combining two polymers</a>.” Clin Ophthalmol. 11, 1637-1642. doi:10.2147/OPTH.S135550. <hr /> |
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