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GloPIPs BODIPY TMR-PtdIns(4, 5)P2, C16
Cat No:C-45M16A 50UG | Brand:Echelon Biosciences
Description
| Pack Size | 50 ug |
|---|---|
| Storage Temperature | -20 degree C or below\, protect from light |
| Note | This product is for research use only. |
| Description | Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4, 5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3, 4, 5)P3. <hr /> GloPIPs are labeled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labeled PIPs has been changed to a more stable amide from an ester. Results from experiments conducted at Echelon indicated that this minor chemical change did not have a significant effect in any of the applications tested. <object id="wobj-318-c-45m16a" type="text/html" data="https://www.bioz.com/v_widget_2_5/318/c-45m16a" style="width:100%; height: 96px; background-color:[RGB Color];"></object> <div id="bioz-w-pb-c-45m16a-div" style="width: 100%;display:none"><a id="bioz-w-pb-c-45m16a" style="font-size: 12px;text-decoration:none;color:transparent;" href="https://www.bioz.com/" target="_blank" rel="noopener noreferrer"><img src="https://cdn.bioz.com/assets/favicon.png" style="width:11px;height:11px;vertical-align: baseline;padding-bottom:0px;margin-left:0px;margin-bottom:0px;float:none;display:none"> Powered by Bioz</a><a style="font-size: 12px;text-decoration:none;float: right;color:transparent;" href="https://www.bioz.com/result/c-45m16a/product/Echelon Biosciences/?cn=c-45m16a" target="_blank" rel="noopener noreferrer"> See more details on Bioz</a></div> Bulk discounts available, please email <a href="mailto:echelon@echelon-inc.com?subject=Bulk">echelon@echelon-inc.com</a> for information. |
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