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Range of ELISA Kits, Antibodies, Biochemicals, Recombinant Proteins & Assay Kits
Description
| Pack Size | 100 ug |
|---|---|
| Storage Temperature | -20 degree C or below |
| Note | This product is for research use only. |
| Description | PI(3, 4, 5)P3 (D-myo-Phosphatidylinositol 3, 4, 5-trisphosphate) 17:0/16:0 is a synthetic PI(3, 4, 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3, 4, 5-trisphosphate (PIP3), formed from PI(4, 5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4, 5)P2 and SHIP to PI(3, 4)P2. Phosphatidylinositol 3, 4, 5-trisphosphate 17:0/16:0 is a synthetic PI(3, 4, 5)P3 analog with an unnatural C17 acyl chain at the sn-1 position. <hr /> <b>Product Keywords: </b>Dipalmitoyl Phosphatidylinositol 3, 4, 5-trisphosphate, PtdIns(3, 4, 5)P3, PI(3, 4, 5)P3 (17:0/16:0), or PIP3 Bulk discounts available, please email <a href="mailto:echelon@echelon-inc.com?subject=Bulk">echelon@echelon-inc.com</a> for information. |
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