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PTH Related protein (1-40); Hypercalcemia Malignancy Factor

Cat No:231-85 1MG | Brand:Echelon Biosciences

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Description

Pack Size 1 mg
Storage Temperature -20 degree C or below
Note This product is for research use only.
Description CAS Number: 120298-73-9 Molecular Weight: 4672.57 Salt Form: TFA Purity: >95% Sequence (3-letter): Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser-OH Sequence (1-letter): AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATS-OH Storage: -20 °C or below PTH Related protein (1-40) is an amino-terminal fragment which induces dose-dependent calcium resorption in rat bone organ culture and calcium uptake in enterocytes. Parathyroid hormone-related protein (PTHrP) is expressed in some human cancers (breast and certain lung cancers) but has normal functions in mammary gland development, tooth eruption, and fetal bone development. Tumor secretion of PThrP can lead to hypercalcemia which can be an initial indication of malignancy.
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