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Z-Ala-Ala-Asp-AFC (Cathepsin S Substrate, fluorogenic)
Cat No:874-06 5MG | Brand:Echelon Biosciences
Description
Pack Size | 5 mg |
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Storage Temperature | -20 degree C or below |
Note | This product is for research use only. |
Description | Molecular Weight: 620.54 Salt Form: N/A Purity: >96% Sequence (3-letter): Z-Ala-Ala-Asp-AFC Sequence (1-letter): (Z)AAD(AFC) Storage: -20 °C or below Z-Ala-Ala-Asp-AFC is a fluorogenic substrate for cathepsin S, a lysosomal cysteine protease with important roles in MHC Class II antigen presentation and nociception. Cathepsin S also cleaves several extracellular matrix proteins (laminin, fibronectin elastin, osteocalcin) and glycosaminoglycans (heparin sulfate, chondroitin sulfate). Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm. |