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Description
| Pack Size | 1 mg |
|---|---|
| Storage Temperature | -20 degree C or below |
| Note | This product is for research use only. |
| Description | Molecular Weight: 880.17 Salt Form: TFA Purity: >95% Sequence (3-letter): N-Myr-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH Sequence (1-letter): (Myristoyl)EAVSLKPT-OH Storage: -20 °C or below Protein kinase C epsilon, PKC(e), is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. This peptide is the myristoylated version of an octapeptide PKC(e) inhibitor (Cat# <a href="https://echelon-inc.com/product/pkc-isoenzyme-inhibitor-pkc-y-translocation-peptide/">880-15</a>). Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH is a selective inhibitor of the translocation of PKC(e). It can be used to resolve the functions of PKC(e) from those of other PKC isozymes. <h4>References</h4> Obis <em>et al.</em> (2015) <a href="https://molecularbrain.biomedcentral.com/articles/10.1186/s13041-015-0098-x">The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.</a> Molecular Brain (8) |
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