
Gene Editing services by Synbio Technologies
We,
Biotechno Labs are pleased to introduce Gene Editing services by Synbio
Technologies. Synbio Technologies is incorporated with a single mission in
mind: to empower scientific discoveries and drug innovation by providing the
most advanced and cost-effective DNA technology platform. The company has
developed a full range of DNA reading (sequencing), DNA writing (synthesis), and DNA editing (engineering)
capabilities and has delivered satisfactory solutions globally to researchers
for various applications, including diagnostic DNA probes, precision medicine,
protein production, antibody discovery, vaccine development, novel enzymes,
molecular breeding, biofuel implication, etc.
CRISPR-Cas is a
microbial adaptive immune system that uses RNA-guided nucleases to cleave
foreign genetic elements. The RNA-guided nuclease function of CRISPR-Cas is
reconstituted in mammalian cells through the heterologous expression of human
codon–optimized Cas9 and the requisite RNA components. Furthermore, the crRNA
and tracrRNA can be fused together to create a chimeric, single-guide RNA
(sgRNA). Cas9 can thus be re-directed toward almost any target of interest in
immediate vicinity of the PAM sequence by altering the 20-nt guide sequence
within the sgRNA. The main applications of CRISPR-Cas technology are Gene
silencing, DNA-free CRISPR-Cas9 gene editing,
Homology-directed repair, Transient gene silencing or transcriptional
repression, Transient activation of endogenous genes, generation of transgenic
animals, Pooled genome-scale knockout screening. mso-fareast-font-family:"Times New Roman"">
CRISPR-Cas9 Services at Synbio technologies: