
Recombinant Human CDH17, partial (Active)
Cadherin-17 (corresponding to CDH17) is a newly discovered member of the cadherin superfamily. Cadherins act as Ca2+-dependent transmembrane glycoproteins that mediate cell-cell adhesion. To date, there is a growing focus on CDH17 in tumors, particularly gastrointestinal cancers (GICs). Some target identification lies at the heart of GIC treatment, like EGFR, HER-2, PD-1, MET, CTLA4, VEGF, DDR1, LAG3, MUC1, TIGIT, and CLDN18.2. CDH17 offers new insights into immunotherapy for tumors, particularly gastrointestinal cancers.