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A 83-01

SKU: BTL-IB-P-00030 | Brand: Isca Biochemical

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Product Description

Cat Number	RK-020
Category	Peptide
Pack Size	5 mg
Description	TGF-βRI, ALK4 and ALK7 inhibitor
Purity	98% by TLC, NMR conforms
Biomarker Target	Receptor serine/threonine kinase receptors
Sequence Three Letter Code	3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Molecular Formula	C25H19N5S
Solubility	Soluble in DMSO to 20 mg/ml
Appearance	Light yellow solid
Storage	Store dry, frozen and in the dark
References	Tojo et al (2005) The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 96(11) 791 PMID: 16271073Li et al (2009) Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell 4(1) 16 PMID: 19097958Chen et al (2015) Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-mediated regeneration. Cardiovasc Res. 105(1) 44 PMID: 25362681 Related areas All small molecules >All receptor serine/threonine kinase receptor modulators >All stem cell research categories >
Note	The product is for research use only

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