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SB 431542

SKU: BTL-IB-P-00003 | Brand: Isca Biochemical

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Product Description

Cat Number	RK-030
Category	Peptide
Pack Size	5 mg
Description	Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
Purity	99% by hplc, NMR conforms
Biomarker Target	Receptor serine/threonine kinase receptors
Sequence Three Letter Code	4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Molecular Formula	C22H16N4O3
References	Laping (2002) Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol Pharmacol. 62(1) 58 PMID: 12065755Halder et al (2005) A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers. Neoplasia 7(5) 509 PMID: 15967103Stanslowsky (2014) Functional differentiation of midbrain neurons from human cord blood-derived induced pluripotent stem cells. Stem Cell Res Ther. 5(2) 35 PMID: 24636737 Related areas All small molecules >All receptor serine/threonine kinase receptor modulators >All stem cell research categories >All cancer research categories >
Note	The product is for research use only

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