Methionine and Choline Deficient L-Amino Acid Diet
SKU: BTL-RDI-AD-00013 |
Brand: Research Diet Inc.
Product Description
| Cat Number | A02082002BR |
|---|---|
| Category | Open Source Purified Diet |
| Pack Size | 12.5 Kg |
| Description | A Methionine and Choline Deficient (MCD) L-Amino Acid Diet is a specialized rodent diet, rich in sugar and fat but lacking essential methionine and choline, used to model human Non-Alcoholic Steatohepatitis (NASH) by inducing rapid fatty liver (steatosis), inflammation, oxidative stress, and fibrosis, mimicking human liver disease progression. The absence of choline impairs fat export (VLDL), while methionine deficiency reduces crucial antioxidants (SAM, GSH), leading to severe liver damage and cellular stress. |
| Specie Reactivity | Rodent (Rat/Mouse); Color: Red |
| Product Url | View Document |
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