HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells
SKU: BTL-AG-A-02976 |
Brand: Accegen
Product Description
| Cat Number | ABC-SC0088T |
|---|---|
| Category | Stem Cells |
| Pack Size | 1 vial |
| Product Description | Human Peripheral Blood Mononuclear Cells (PBMC) are blood cells with a single round nucleus. These cells include lymphocytes (T, B and NK cells), monocytes and dendritic cells. Mononuclear cells are parts of the immune system which is critical for cell-mediated and humoral immunity. Mobilized peripheral blood is collected after the donor is treated with mobilization agent such as G-CSF. Such treatment mobilizes blood stem cells that are normally reside in the bone marrow to enter the blood stream. The content of CD34+ stem cells in the blood is therefore the most important parameter of graft quality. The optimal CD34+ cell dose is widely accepted to be 5 × 106/kg. Particularly, the more primitive CD34+/CD38-subset has been shown to have high self-renewal and repopulation capability. Stem cell mobilization also affects the properties of other components of the graft such as T lymphocytes and NK cells. AcceGen Human Mobilized PBMCs are isolated from healthy donors that have been mobilized with GCSF collected in acid-citrate-dextrose formula A (ACDA) as an anticoagulant. All donors must be tested negative for HBV, HCV and HIV and are IRB consented. |
| Specie Reactivity | Human |
| Note | The product is for research use only |
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