Product Description
| Cat Number | ABC-TC5562 |
|---|---|
| Category | Tumor Cell Lines |
| Pack Size | 1 vial |
| Product Description | The multi drug-resistant cell line MES-SA/Dx5 was derived from the human uterine sarcoma cell line MES-SA which was originally obtained from a tumour from a 56-year-old Caucasian female at the time of hysterectomy. The Dx5 variant exhibits a 100-fold resistance to Adriamycin and has a reported doubling time of 30 hours. The two additional marker chromosomes indicate clonal selection during drug selection. MES-SA/Dx-5 cells exhibit marked cross-resistance to a number of chemotherapeutic agents (including daunorubicin, dactinomycin, vincristine, taxol, colchicine) and moderate cross-resistance to MMC and melphalan. |
| Specie Reactivity | Human |
| Note | The product is for research use only |
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