Rat Activin RIIA/ACVR2A Protein (ARA-RM12A)
SKU: BTL-KB-P-00194 |
Host: Rat |
Brand: Kactus Bio
Product Description
| Cat Number | ARA-RM12A |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Rat Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Pro135. |
| Target | Activin RIIA/ACVR2A |
| Host | Rat |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer. |
| Molecular Mass | The protein has a predicted MW of 15.06 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala20-Pro135 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P38444 |
| Amino Acid Sequence | Recombinant Rat Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Pro135. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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