SARS-COV-2 Spike S1 (Deltacron) Protein (COV-VM1SD)
SKU: BTL-KB-P-01085 |
Host: SARS-COV-2 |
Brand: Kactus Bio
Product Description
| Cat Number | COV-VM1SD |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant SARS-COV-2 Spike S1(Deltacron) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H). Alanine substitutions (R683A) are introduced to stabilize the trimeric prefusion state of SARS-COV-2 Spike S1(Deltacron) Protein and abolish the furin cleavage site, respectively. |
| Target | Spike S1 |
| Host | SARS-COV-2 |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
| Molecular Mass | The protein has a predicted MW of 73.94 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H) |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | QHD43416.1 |
| Amino Acid Sequence | Recombinant SARS-COV-2 Spike S1(Deltacron) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln14-Arg683(T19R, A27S, T95I, G142D, EFR156G, NL211I, INS214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H). Alanine substitutions (R683A) are introduced to stabilize the trimeric prefusion state of SARS-COV-2 Spike S1(Deltacron) Protein and abolish the furin cleavage site, respectively. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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