Product Description
| Cat Number | HF543016 |
|---|---|
| Category | Biosimilar |
| Pack Size | 100 ug |
| Description | ANB020,nowcalledetokimab,iscurrentlyinphase2atestingineczema,whichisalsoknownasatopicdermatitis.ScientistsfromtheMedicalResearchCouncilHumanImmunologyUnitattheUniversityofOxfordreleaseddatafrom12patientsshowingthat83%whoweretreatedwithetokimabreportedareductionindiseaseseverityafter29days.Etokimab,ananti-IL-33biologic,haspreviouslydemonstratedagoodsafetyprofileandfavorablepharmacodynamicpropertiesinmanyclinicalstudies.Etokimabisdesignedtoblockinterleukin-33(IL-33),animmune-signalingmolecule.Inpeanutallergy,thebodyoverreactstopeanutsasIL-33activatesanantibodycalledimmunoglobinE.Theseantibodiescauseallergicresponsesuchasmouthitchiness,hives,breathingdifficultiesandpotentiallyfatalanaphylacticshock. |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | NF-HEV,IL-1F11,C9orf26,IL-33,Interleukin-1familymember11,IL33,Nuclearfactorfromhighendothelialvenules,NFHEV,Interleukin-33,IL1F11 |
| Clonality | Monoclonal |
| Synonyms | ANB020,CAS:2022981-44-6,IL33 |
| Host | Humanized |
| Concentration | 1mg/ml |
| Isotype | IgG1-kappa |
| Form | Liquid |
| Purity | >95% as determined by SDS-PAGE. |
| Specie Reactivity | Human |
| Storage | 0.01M PBS, pH7.4. |
| Note | The product is for research use only |
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