Product Description
| Cat Number | HY257146 |
|---|---|
| Category | Biosimilar |
| Pack Size | 100 ug |
| Description | GlofitamabisaT-cell-engagingbispecificantibodypossessinganovel2:1structurewithbivalencyforCD20onBcellsandmonovalencyforCD3onTcells.Glofitamabisaninvestigational,T-cellbispecificantibodywithadistinctivedesignthatfeatures2FabarmsforbindingCD20onBcells,alongwith1FabarmforbindingCD3onTcells.TheCD3bindingarmisfuseddirectlytooneoftheCD20-bindingarmsinahead-to-tailfashionviaashortflexiblelinker. |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | B-lymphocytesurfaceantigenB1,Membrane-spanning4-domainssubfamilyAmember1,MS4A1,LeukocytesurfaceantigenLeu-16,B-lymphocyteantigenCD20,Bp35,CD20,T3E,T-cellsurfaceantigenT3/Leu-4epsilonchain,CD3e,CD3E,T-cellsurfaceglycoproteinCD3epsilonchain |
| Clonality | Monoclonal |
| Synonyms | Bispecific,CD20-TCB(2:1),RG-6026,CAS:2229047-91-8 |
| Host | Humanized |
| Concentration | 1.06mg/ml |
| Isotype | IgG1-kappa-lambda |
| Form | Liquid |
| Purity | >95% as determined by SDS-PAGE. |
| Specie Reactivity | Human |
| Storage | 0.01M PBS, pH7.4. |
| Note | The product is for research use only |
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