Product Description
| Cat Number | T0459 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cyclic guanosine monophosphate-phosphodiesterase (cGMP-PDE), an enzyme that inhibits the normal apoptosis signal pathway; this inhibition permits the apoptotic signal pathway to proceed unopposed, resulting in apoptotic cell death. |
| Molecular Weight | 356.41 |
| Purity | 0.9949 |
| Formula | C20H17FO3S |
| Smiles | C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(S(C)=O)C=C3 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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