Product Description
| Cat Number | T1006 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
| Molecular Weight | 448.4 |
| Purity | 0.95 |
| Formula | C23H30BrNO3 |
| Smiles | [Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc2ccccc12)C(C)C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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