Product Description
| Cat Number | T1024 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling. |
| Molecular Weight | 403.21 |
| Purity | 0.9976 |
| Formula | C17H14Cl2F2N2O3 |
| Smiles | O(CC1CC1)C2=C(OC(F)F)C=CC(C(NC=3C(Cl)=CN=CC3Cl)=O)=C2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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