Product Description
| Cat Number | T10534 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. It exhibits activity against the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM), and EGFR wt (IC50=190 nM). BI-4020 also shows high kinome selectivity and good DMPK properties. |
| Molecular Weight | 542.68 |
| Purity | 0.9844 |
| Formula | C30H38N8O2 |
| Smiles | C[C@@H]1CCCOc2c(cnn2C)-c2cc(cc(C)n2)C(=O)\N=C2/Nc3ccc(CN4CCN(C)CC4)cc3N2C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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