Product Description
| Cat Number | T10896L |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor), with a Kd of 7.43 µM in SPR assays, directly binding to the OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP and is well tolerated in the mouse model of prostate cancer [1]. |
| Molecular Weight | 291.69 |
| Purity | 0.9947 |
| Formula | C10H14ClN3O5 |
| Smiles | Cl.NC(CO)C(=O)N\N=C\c1ccc(O)c(O)c1O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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