Product Description
| Cat Number | T10898 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects. |
| Molecular Weight | 430.97 |
| Purity | 0.998 |
| Formula | C22H31ClN6O |
| Smiles | Cl.CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@H]3CCNC[C@@H]3O)nc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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