Product Description
| Cat Number | T10936 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM. It specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 values of 5 µM and 8 µM, respectively. D-I03 also inhibits the growth of BRCA1 and BRCA2 deficient cells and prevents the formation of damage-induced RAD52 foci, but does not affect RAD51 foci induced by Cisplatin. |
| Molecular Weight | 428.64 |
| Purity | 0.9904 |
| Formula | C23H36N6S |
| Smiles | CCN(CC)CCNC(=S)Nc1ccc2nc(cc(C)c2c1)N1CCN(CC)CC1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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