Product Description
| Cat Number | T11157L |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR, with 100-fold selectivity over wild-type EGFR. It exhibits potent antitumor and antiproliferative activity in H1975 cells and mutant HCC827 cells with IC50s of 4 and 28 nM, respectively. |
| Molecular Weight | 551.04 |
| Purity | 0.998 |
| Formula | C28H31ClN6O4 |
| Smiles | Cl.O=C(C=C)NC1=CC=CC(=C1)N2C(=O)C=C(C=3C=NC(=NC32)NC4=CC=C(OCCN(C)C)C=C4OC)C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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