Product Description
| Cat Number | T11230 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | ERRα antagonist-1 (ERR+/- antagonist-1) is a high-affinity, selective antagonist of the estrogen-related receptor α (ERRα). It effectively prevents the interaction of ERRα with both Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, displaying IC50 values of 170 nM and 180 nM, respectively. Notably, ERRα antagonist-1 does not interfere with the interactions involving ERRβ or ERRγ and the PGC-1α and PGC-1β coactivators. Furthermore, it does not affect the interaction between either ERα or ERβ and PGC-1α or SRC-1. |
| Molecular Weight | 377.53 |
| Purity | 1 |
| Formula | C21H19N3S2 |
| Smiles | C1CN=C(S1)N1CCS\C1=N/C1c2ccccc2C=Cc2ccccc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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