Product Description
| Cat Number | T11699 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. |
| Molecular Weight | 655.44 |
| Formula | C30H37Cl2IN2O2 |
| Smiles | [I-].CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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