Product Description
| Cat Number | T11807 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By blocking histone acetylation, p53 acetylation, and STAT3 activation, L002 shows potential in the treatment of hypertension‐induced cardiac hypertrophy and fibrogenesis. |
| Molecular Weight | 321.35 |
| Purity | 0.9859 |
| Formula | C15H15NO5S |
| Smiles | COc1ccc(cc1)S(=O)(=O)ON=C1C=C(C)C(=O)C(C)=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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