Product Description
| Cat Number | T1185 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2. |
| Molecular Weight | 314.36 |
| Purity | 0.9994 |
| Formula | C17H14O4S |
| Smiles | O=C1C(=C(CO1)C2=CC=C(S(C)(=O)=O)C=C2)C3=CC=CC=C3 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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