Product Description
| Cat Number | T12848 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting UII-induced inflammatory mediators, such as adhesion molecules, in human vascular endothelial cells and upregulation of cytokines and tissue factors. SB 657510 has a therapeutic effect on diabetes-related atherosclerotic disease in diabetic mouse models. |
| Molecular Weight | 505.81 |
| Purity | 0.9803 |
| Formula | C19H22BrClN2O5S |
| Smiles | COc1cc(Br)c(cc1OC)S(=O)(=O)Nc1ccc(Cl)c(O[C@@H]2CCN(C)C2)c1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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