Product Description
| Cat Number | T13063 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | T6167923 is a potent, selective inhibitor of MyD88-dependent signaling pathways. It achieves this by directly binding to the Toll/IL1 receptor (TIR) domain of MyD88, preventing MyD88 homodimer formation. Subsequently, T6167923 impedes NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity and boasts improved anti-inflammatory effects, with IC50s values of 2.7 μM for IFN-γ, 2.9 μM for IL-1β, and 2.66 μM each for IL-6 and TNF-α, demonstrating its efficacy across multiple inflammatory mediators [1]. |
| Molecular Weight | 458.39 |
| Purity | 0.9923 |
| Formula | C17H20BrN3O3S2 |
| Smiles | C[C@H](NC(=O)N1CCN(CC1)S(=O)(=O)c1cccc(Br)c1)c1cccs1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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