Product Description
| Cat Number | T1415 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfibrozil is a fibric acid derivative with hypolipidemic effects. This enhances triglyceride-rich lipoprotein clearance and reduces the expression of apolipoprotein C-III (apoC-III). The reduction in hepatic production of apoC-III result in the subsequent reduction of serum levels of very-low-density-lipoprotein cholesterol (VLDL-C). In addition, gemfibrozil-mediated PPARalpha stimulation of apoA-I and apoA-II expression results in an increase in high-density lipoprotein cholesterol (HDL-C). |
| Molecular Weight | 250.33 |
| Purity | 0.999 |
| Formula | C15H22O3 |
| Smiles | CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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