Product Description
| Cat Number | T14214 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks (Kis of 4 nM, 6 nM, 2 nM, and 1 nM for PI3Kα, β, δ, and γ, respectively), exhibiting anti-tumor activity in a mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K signaling as indicated by a decrease in p-Akt (Ser473). |
| Molecular Weight | 517.58 |
| Purity | ≥98% |
| Formula | C22H28FN9O3S |
| Smiles | COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)[C@H](C)N2CCN(CC2)S(C)(=O)=O)cc1F |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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