Product Description
| Cat Number | T14313 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance. |
| Molecular Weight | 229.26 |
| Purity | 1 |
| Formula | C8H11N3O3S |
| Smiles | O=C1N([C@@H]2S[C@H](CO)OC2)C=CC(N)=N1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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