Product Description
| Cat Number | T1448L |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations. |
| Molecular Weight | 506.03 |
| Purity | 0.9989 |
| Formula | C22H28ClN7O3S |
| Smiles | n1cc(sc1Nc1nc(nc(N2CCN(CC2)CCO)c1)C)C(=O)Nc1c(cccc1C)Cl.O |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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