Product Description
| Cat Number | T14680 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively. |
| Molecular Weight | 556.5 |
| Purity | 0.9987 |
| Formula | C26H26F6N4O3 |
| Smiles | CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O)C1=O)c1ccccc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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