Product Description
| Cat Number | T14687 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor for the treatment of autoimmune diseases. It blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain, inhibiting IL-12/23 and type I IFN pathways. It selectively binds to the TYK2 pseudokinase (JH2) domain with an IC50 of 1.0 nM. |
| Molecular Weight | 425.46 |
| Purity | 0.9943 |
| Formula | C20H19D3N8O3 |
| Smiles | [2H]C([2H])([2H])NC(=O)c1nnc(NC(=O)C2CC2)cc1Nc1cccc(-c2ncn(C)n2)c1OC |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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