Product Description
| Cat Number | T14775 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase. |
| Molecular Weight | 289.16 |
| Purity | 0.9847 |
| Formula | C11H6F3NO5 |
| Smiles | COc1ccc2oc(cc(=O)c2c1[N+]([O-])=O)C(F)(F)F |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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