Product Description
| Cat Number | T15096 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Delgocitinib (JTE-052) is a specific JAK (Janus kinase) inhibitor with IC50 values of 2.8, 2.6, 13, and 58 nM for JAK1, JAK2, JAK3, and Tyk2 respectively. Delgocitinib is involved in various inflammatory and autoimmune diseases through JAK-dependent cytokines and can effectively suppress multiple cytokine signaling while inhibiting itching caused by cytokines. It is widely used to treat various inflammatory diseases, including autoimmune diseases and hypersensitivity reactions. |
| Molecular Weight | 310.35 |
| Purity | 0.999 |
| Formula | C16H18N6O |
| Smiles | C[C@H]1CN(C(=O)CC#N)[C@]11CCN(C1)c1ncnc2[nH]ccc12 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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