Product Description
| Cat Number | T1562 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense. |
| Molecular Weight | 370.79 |
| Purity | 0.999 |
| Formula | C19H15ClN2O4 |
| Smiles | OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C1=CC=C(Cl)C=C1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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