Product Description
| Cat Number | T15641 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | K777 is a potent, orally active, and irreversible inhibitor of cysteine protease, functioning as a potent CYP3A4 inhibitor (IC50 = 60 nM) and a selective CCR4 antagonist, which inhibits chemotaxis. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypanosoma cruzi, and cathepsins B and L, targeting cathepsin-mediated cell entry and exhibiting broad-spectrum antiviral activity. It inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87 nM and 0.68 nM, respectively. |
| Molecular Weight | 574.73 |
| Purity | 0.9914 |
| Formula | C32H38N4O4S |
| Smiles | CN1CCN(CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCc1ccccc1)\C=C\S(=O)(=O)c1ccccc1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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