Product Description
| Cat Number | T15738 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Lestaurtinib (CEP 701) is an orally available and selective inhibitor of FMS-like tyrosine kinase-3 (FLT3, IC50: 0.9 nM), which inhibits FLT3 autophosphorylation in vitro.Lestaurtinib promotes the expression of c-MYC, inhibits the phosphorylation of RPTKs, and has high affinity for TrkA and JAK2. Lestaurtinib promotes c-MYC expression, inhibits phosphorylation of RPTKs, has a high affinity for TrkA and JAK2, induces apoptosis and cell growth arrest, and can be used to study leukemia. |
| Molecular Weight | 439.46 |
| Purity | 0.9917 |
| Formula | C26H21N3O4 |
| Smiles | C[C@]12N3C=4C=5N(C=6C(C5C7=C(C4C=8C3=CC=CC8)CNC7=O)=CC=CC6)[C@](O1)(C[C@@]2(CO)O)[H] |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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