Product Description
| Cat Number | T1600 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand. |
| Molecular Weight | 246.19 |
| Purity | 0.9981 |
| Formula | C9H11FN2O5 |
| Smiles | O[C@H]1[C@@H](O[C@H](C)[C@H]1O)N2C(=O)NC(=O)C(F)=C2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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