Product Description
| Cat Number | T16345 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | NS13001 (N-(4-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias. |
| Molecular Weight | 353.81 |
| Purity | 0.9955 |
| Formula | C17H16ClN7 |
| Smiles | Cc1cc(C)n(n1)-c1nc(Nc2ccc(Cl)cc2)c2ncn(C)c2n1 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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