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PKR-IN-C16

SKU: BTL-TM-B-04541 | Brand: Target Mole
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Product Description

Cat Number T16550
Category Biochemical
Pack Size 1EA
Description PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.
Molecular Weight 268.29
Purity 0.978
Formula C13H8N4OS
Smiles O=C1Nc2ccc3ncsc3c2\C1=C\c1cnc[nH]1
Storage -20 ℃
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Note This product is for Research Use Only
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