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RG-12525

SKU: BTL-TM-B-04622 | Brand: Target Mole
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Product Description

Cat Number T16739
Category Biochemical
Pack Size 1EA
Description RG-12525(NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM, and 7 nM, respectively.RG-12525 inhibits CYP3A4, with a Ki value of 0.5 µM. RG-12525 is a novel and potent PPAR-γ agonist (IC50 value of about 60 nM) with species specificity for the study of asthma.
Molecular Weight 423.47
Purity 0.9677
Formula C25H21N5O2
Smiles N1=NNC(=N1)CC=2C=CC=CC2COC3=CC=C(OCC4=NC=5C=CC=CC5C=C4)C=C3
Storage -20 ℃
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Note This product is for Research Use Only
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