Product Description
| Cat Number | T16750 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Rigosertib (ON-01910) is a selective, non-ATP-competitive PLK1 inhibitor (IC50: 9 nM) and multi-kinase inhibitor. As a selective anti-cancer agent, Rigosertib induces apoptosis by inhibiting the PI3 kinase/Akt pathway, promotes histone H2AX phosphorylation, and induces G2/M arrest in the cell cycle. |
| Molecular Weight | 451.49 |
| Purity | 0.9733 |
| Formula | C21H25NO8S |
| Smiles | C(=C/S(CC1=CC(NCC(O)=O)=C(OC)C=C1)(=O)=O)\C2=C(OC)C=C(OC)C=C2OC |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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