Product Description
| Cat Number | T201415 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | MGD-28 is a potent, orally active Cullin-CRBN-dependent IKZF family protein degrader that dose-dependently degrades IKZF1 (Ikaros), IKZF2 (Helios), and IKZF3 (Aiolos) at nanomolar strengths.MGD-28 also degrades CK1α, and has shown antiproliferative activity against a variety of hematologic cancer cell lines showing antiproliferative activity in vitro and antitumor effects in in vivo assays, and is commonly used in multiple myeloma (MM) and hematological disorders. |
| Molecular Weight | 595.67 |
| Formula | C33H34FN7O3 |
| Smiles | N#CC1=CC=C(C=C1F)N2CCN(CC3=CC=C(C=C3)CNC4=CC=CC=5C(=O)N(N(C)CC45)C6C(=O)NC(=O)CC6)CC2 |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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