Product Description
| Cat Number | T2064 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), exhibiting a 20-fold greater selectivity for VEGFR2 over PDGFRβ, with no activity against InsR, EGFR, and FGFR. Semaxinib reversibly inhibits ATP binding to the tyrosine kinase domain of VEGFR2, potentially inhibiting VEGF-stimulated endothelial cell migration and proliferation, thereby reducing tumor microvasculature. |
| Molecular Weight | 238.28 |
| Purity | 0.9984 |
| Formula | C15H14N2O |
| Smiles | C(=C1C=2C(NC1=O)=CC=CC2)C=3NC(C)=CC3C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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