Product Description
| Cat Number | T21637 |
|---|---|
| Category | Biochemical |
| Pack Size | 1EA |
| Description | SB-505124 hydrochloride (SB505124 hydrochloride) is an orally available, selective and potent inhibitor of TGF-β type I receptors (ALK4, ALK5, ALK7) with IC50 values of 129 nM and 47 nM for ALK4 and ALK5, respectively. SB-505124 hydrochloride inhibits IL-6 production by synovial explants and reduces Th17 differentiation in mice by decreasing Il17a and Rorc gene expression and IL-17 protein production.SB-505124 hydrochloride is used in the study of colorectal cancer. |
| Molecular Weight | 371.86 |
| Purity | 0.9871 |
| Formula | C20H22ClN3O2 |
| Smiles | Cl.N=1C(=CC=CC1C)C=2N=C(NC2C=3C=CC=4OCOC4C3)C(C)(C)C |
| Storage | -20 ℃ |
| View Document | |
| Note | This product is for Research Use Only |
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